A Restless Bunch

Oncologists and other cancer doctors decide what type of treatment to prescribe to each patient. There are many options. There are no universal treatment regimen for pleural mesothelioma cancer sufferers. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.

The prospects for mesothelioma patients have been grim, but doctors have recently made progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) There are problems with all three. Patients with mesothelioma have not responded well to traditional radiation therapy. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.

The mesothelial tissue around the tumor is removed by surgery. This surgery is extensive and it is not clear how much the patient benefits. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. As with radiation, research is going toward controlling the physical location of the treatment with emphasis on the pleural cavity.

Many advanced techniques in cancer treatment are tried on mesothelioma patients because of its high fatality rate. Such treatments include anti-angiogenesis drugs like thalidomide and biologic therapies agent interleukin 2. Pemetrexed (Alimta) is a new drug that has shown results in extending life.

Before acting, oncologists review the stage of mesothelioma, position of the tumor, and age and health status of the patient. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.